This is a resource for animal researchers completing an alternatives search for an IACUC protocol.
More information about the McDaniel IACUC can be found on the portal: https://iammcdaniel.sharepoint.com/sites/IACUC
If you need assistance in formulating an effective search, consult with the library!
Searching for animal alternatives is typically guided by the "3 R's":
- Reduction - Minimize the number of animals used to smallest number needed to obtain statistically relevant results.
- Refinement - Use techniques that reduce the incidence or severity of pain and/or distress in animals.
- Replacement - Substitution of non-animal methods or material or a lower species that may be less sensitive to pain and distress.
Use the tabs in the left column to navigate to information on
- determining keywords and terminology to search
- developing appropriate search strategies
- determining core and alternative databases to search
- writing the literature review and lay summary sections of the protocol